Which pathogen is commonly associated with aggressive periodontitis?

Aggressive periodontitis is primarily associated with Aggregatibacter actinomycetemcomitans. This bacterium is known for its capacity to cause localized aggressive periodontitis, particularly in adolescents and young adults. Its virulence factors, such as the production of leukotoxin, contribute to the destruction of periodontal tissues and bone loss, distinguishing it as a key pathogen in the disease process.

In contrast, while Porphyromonas gingivalis (another choice) is significantly involved in chronic periodontitis and has been implicated in various forms of periodontal disease, it is not the primary pathogen associated with aggressive periodontitis. Other pathogens like Streptococcus mutans and Rothia mucilaginosa are more linked to dental caries and general oral microbiota rather than specifically to aggressive forms of periodontal disease. Thus, the association of Aggregatibacter actinomycetemcomitans with aggressive periodontitis highlights its particular role in this condition.