What effect does keratinization have on epithelial cells?

Keratinization refers to the process by which epithelial cells accumulate keratin, a tough, protective protein. This process plays a crucial role in the integrity and function of the skin and mucosal surfaces. When epithelial cells undergo keratinization, they become stronger and more resistant to physical and chemical insults. The accumulation of keratin adds an additional layer of protection that helps to prevent water loss from the body, thereby making these cells waterproof.

In areas such as the gingiva in the oral cavity, keratinized tissue is vital for maintaining health and protecting against mechanical stresses, such as those from mastication. Keratinization also contributes to the barrier function of epithelial cells, enhancing their role in protecting against pathogens and substances that could lead to inflammation or infection.

Because of these protective features, keratinized cells are indeed more robust compared to their non-keratinized counterparts, making this response a critical aspect of tissue resilience and overall oral health.